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An effort by the Villani, Kharchenko, Gehlenborg, Theis, Marioni, and Regev labs.

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Single-cell RNA-seq reveals the cell-type-specific molecular and genetic associations to lupus

Multiplexed scRNA-seq of 1.2 million PBMCs from adult lupus samples

Multiplexed scRNA-seq of 1.2 million PBMCs from adult lupus samples

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Cell Metadata

author_cell_type

NK

Ontology Term: natural killer cellCL:0000623
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: large granular lymphocyte, null cell, NK cell
CategoryClass of which the cell type is a subclass.: group 1 innate lymphoid cellCL:0001067
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: GNLY, KLRB1, NKG7, PRF1
Canonical Marker Genes: unknown
Rationale: NA

Inherited from author_cell_type

Set of Labels Description: 1.2 million PBMCs from 162 SLE cases and 99 healthy controls of either Asian or European ancestry were profiled using mux-seq.
Annotation Method: manual