B cells were identified via RCAv2, as well as via cell population-specific integration and sub-clustering. These B cells either had heightened levels of platelet marker gene expression, or could not be confidently annotated as a specific B cell subtype.
Inherited from author_cell_type
Set of Labels Description
These author cell type labels were assigned largely at the per-cluster level. We identified broad cell types using RCAv2-based clustering (B, CD34+ haematopoietic stem and progenitor cell (HSPC), myeloid, natural killer (NK), plasma cell, plasmacytoid dendritic cell (pDC), platelet, and T). We then performed cell population-specific (B; myeloid + pDC; CD4+ T and dnT; non-CD4+ T and NK and ILC) integration (Seurat RPCA) and sub-clustering (Louvain clustering), and annotated clusters based on their marker genes.
