- SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.
- lymph node centroblast, germinal center dark zone B cell
- CategoryClass of which the cell type is a subclass.
- germinal center B cellCL:0000844
- Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.
- CD79B, STMN1, MKI67, POU2AF1, AICDA
- Canonical Marker Genes
- BCL6, CXCR4, AID, CD10, CD38, CD77
- Rationale
- CD79B shows these are B cells
POU2AF1 and AICDA are germinal center markers for B cells, and AICDA points towards dark zone.
proliferation markers MKI67 and stathmin (STMN1) upregulated when compared to other B cell clusters show these have more of a proliferating signature, which points to dark zone B cells.