B
- SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.
- B-cell, B-lymphocyte, B lymphocyte
- CategoryClass of which the cell type is a subclass.
- B cellCL:0000236
- Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.
- HLA-DRA, CD74, CD79A, MS4A1
- Rationale
- Expression of major histocompatibilty complex II (HLA-DRA), BCR protein CD79A, MS4A1, which couples to both BCR and HLA, and CD74, which is in the BCR signaling pathway
Inherited from celltype
- Set of Labels Description
- In this paper we used an automated iterative subclustering algorithm to find hundreds of cell state clusters, after which we merged unsupported clusters and annotated each resulting cluster with a better-known cell subtype. The high-res cell state clusters are annotated as subtype.gene1.gene2, so in some cases we didn't directly name some commonly named subtypes, such as pericytes. When we run DE on the resulting subtypes, we find many canonical and scRNA-suggested marker genes.
- Annotation Method
- both
- Algorithm Name
- ARBOL
- Algorithm Version
- v1.0
- Algorithm URL
- https://github.com/jo-m-lab/ARBOL/