- Ontology Term
- conventional dendritic cellCL:0000990
- SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.
- cDC, dendritic reticular cell, DC1, type 1 DC, veiled cell, interdigitating cell, cDC1
- CategoryClass of which the cell type is a subclass.
- dendritic cellCL:0000451
- Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.
- HLA-DPB1, HLA-DRA, LYZ, CST3, XCR1, CD74, CLEC9A
- Canonical Marker Genes
- HLA-D---, ITGAX/CD11c, XCR1
- Rationale
- These are clear dendritic cells based on HLA, CD74 (MHC class 2 presentation molecules) and because they display increased XCR1 when compared to all other myeloid cells, we call them cDC1, because this is the marker that differentiates from cDC2