- SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.
- CD27-positive, CD38-positive, CD20-negative B cell, CD20-negative B cell
- CategoryClass of which the cell type is a subclass.
- plasmablastCL:0000980
- Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.
- XBP1, MZB1, DERL3, CENPA, PCLAF, JCHAIN, TOP2A
- Canonical Marker Genes
- XBP1, MZB1, TOP2A, DERL3
- Rationale
- Cells within this cluster are clearly proliferative plasmablasts with high expression levels of proliferation-related genes (H2AFZ, TUBA1B, MKI67 and TOP2A, among others). Otherwise have an expression pattern of PCs (the 3 transcription factors PRDM1, IRF4 and XBP1, as well as phenotypic markers MZB1, SLAMF7, SSR4, CREB3L2 and FKBP11).