- Ontology Term
- CD16-negative, CD56-bright natural killer cell, humanCL:0000938
- SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.
- CD56-bright cytokine secreting NK cell, CD16-negative, CD56-bright NK cell, CD16-CD56bright NK cell, CD56-bright cytokine secreting natural killer cell
- CategoryClass of which the cell type is a subclass.
- natural killer cellCL:0000623
- Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.
- KLRF1, GNLY, KLRD1, NKG7, NCAM1, EOMES, AREG
- Canonical Marker Genes
- KLRF1, GNLY, KLRD1, NKG7, NCAM1, EOMES, AREG
- Rationale
- These cells have an immunoregulatory function, possess a strong ability to react to cytokine stimulation, are mainly found in secondary lymphoid organs, and have limited cytotoxic capacity. They are the precursors of CD16+CD56- NK cells.