snRNA-seq of human retina - retinal ganglion cell subset

Main

Cell Metadata

PG_OFF

Full Name: OFF parasol RGC
Closest Ontology Term: parasol ganglion cell of retinaCL:4023189
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: M cell, M ganglion cell
Category Class of which the cell type is a subclass.: retinal ganglion cellCL:0000740
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: C8orf34, MGAT5B, WWC1, PLCL1, PROX1, HPGD, COL24A1, GRIP2
Canonical Marker Genes: FABP4
Rationale: 99.7%PG-OFF of the Sanes dataset; 96.9%RGC4 of the Shekhar dataset; 88.7%PG_OFF+11.3%Unassigned of the macaque dataset; 52.1%12_ooDS_NT+41.0%Unassigned of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: A total of 11 retinal ganglion cell clusters were identified from over 399K retinal ganglion cell nuclei in the current atlas. Utilizing previously characterized markers from macaque, 5 clusters can be annotated.
Annotation Method: manual

Full Name: OFF parasol RGC
Closest Ontology Term: parasol ganglion cell of retinaCL:4023189
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: M cell, M ganglion cell
Category Class of which the cell type is a subclass.: retinal ganglion cellCL:0000740
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: C8orf34, MGAT5B, WWC1, PLCL1, PROX1, HPGD, COL24A1, GRIP2
Canonical Marker Genes: FABP4
Rationale: 99.7%PG-OFF of the Sanes dataset; 96.9%RGC4 of the Shekhar dataset; 88.7%PG_OFF+11.3%Unassigned of the macaque dataset; 52.1%12_ooDS_NT+41.0%Unassigned of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: A total of 11 retinal ganglion cell clusters were identified from over 399K retinal ganglion cell nuclei in the current atlas. Utilizing previously characterized markers from macaque, 5 clusters can be annotated.
Annotation Method: manual