snRNA-seq of human retina - amacrine cell subset

HAC48

Ontology Term

GABAergic amacrine cellCL:4030027

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

amacrine cell, GABAergic

Category

Class of which the cell type is a subclass.

amacrine cellCL:0000561

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

MPP6, SEMA3D, AF279873.3, LINC00842, BMPER, ADAMTS9-AS2, PTH2R, CPAMD8, ATP8B4, SHISA9

Canonical Marker Genes

unknown

Rationale

100.0%Gaba12 of the Sanes dataset; 100.0%Unassigned of the macaque dataset; 97.0%AC20 of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Inherited from author_cell_type

Set of Labels Description

Over 89 amacrine cell types were identified among over 571K amacrine nuclei in the current atlas. These 89 cell types can be categorized into GABAergic amacrine cells, Glycinergic amacrine cells, and Both type using marker genes, specifically the GABA-synthetic enzymes GAD1 and GAD2, and the glycine transporter SLC6A9. Based on previously characterized markers, 14 of the 89 amacrine cell clusters could be annotated as known amacrine types.

Annotation Method

manual