Single Cell Atlas of Human Ocular Surface scRNA-seq: Cornea, Limbus, Sclera

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Cell Metadata

Pericytes

Ontology Term: pericyteCL:0000669
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: adventitial reticular cell, ARC, cell of Rouget, pericyte cell, pericyte of Rouget
Category Class of which the cell type is a subclass.: mural cellCL:0008034
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: C11orf96, TAGLN, IGFBP7, CALD1, TPM2, ID4, PTMA, EPS8, COL4A2, MYL9
Canonical Marker Genes: RGS5, ACTA2
Rationale: 99.0% PeC from Shi dataset; 98.7% fibroblastic corneal endothelial cells from Lako adult dataset;79.0% myofibroblasts from Lako fetal dataset; majorclass annotated by RGS5, ACTA2, low expression of DES

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual

Ontology Term: pericyteCL:0000669
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: adventitial reticular cell, ARC, cell of Rouget, pericyte cell, pericyte of Rouget
Category Class of which the cell type is a subclass.: mural cellCL:0008034
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: C11orf96, TAGLN, IGFBP7, CALD1, TPM2, ID4, PTMA, EPS8, COL4A2, MYL9
Canonical Marker Genes: RGS5, ACTA2
Rationale: 99.0% PeC from Shi dataset; 98.7% fibroblastic corneal endothelial cells from Lako adult dataset;79.0% myofibroblasts from Lako fetal dataset; majorclass annotated by RGS5, ACTA2, low expression of DES

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual