Single Cell Atlas of Human Ocular Surface scRNA-seq: Cornea, Limbus, Sclera

Main

Cell Metadata

Epi-TDC/PMC

Ontology Term: epithelial cellCL:0000066
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: epitheliocyte
CategoryClass of which the cell type is a subclass.: eukaryotic cellCL:0000255
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: EZR, LYPD3, DSP, CLDN1, APOBEC3A, SFN, TACSTD2, DSC2, MAL2, CLDN4
Canonical Marker Genes: unknown
Rationale: all from chen_cornea and chen_limbus, show the status between PMC and TDC; majorclass annotated by KRT5; from Epi-PMC, Epi-TDC/PMC, to Epi-TDC, KRT3 and KRT12 expression increase

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual

Ontology Term: epithelial cellCL:0000066
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: epitheliocyte
CategoryClass of which the cell type is a subclass.: eukaryotic cellCL:0000255
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: EZR, LYPD3, DSP, CLDN1, APOBEC3A, SFN, TACSTD2, DSC2, MAL2, CLDN4
Canonical Marker Genes: unknown
Rationale: all from chen_cornea and chen_limbus, show the status between PMC and TDC; majorclass annotated by KRT5; from Epi-PMC, Epi-TDC/PMC, to Epi-TDC, KRT3 and KRT12 expression increase

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual