Single Cell Atlas of Human Ocular Surface scRNA-seq: Cornea, Limbus, Sclera

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Cell Metadata

LPC

Ontology Term: progenitor cellCL:0011026
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: unknown
CategoryClass of which the cell type is a subclass.: precursor cellCL:0011115
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: KRT15, KRT14, S100A2, CXCL14, RPLP1, MIR205HG, DST, AQP3, MT1X, SLC6A6
Canonical Marker Genes: KRT15
Rationale: 81.5% limbal progenitor cells+50.8% melanocytes from Lako adult dataset;9.1% corneal epithelium from Lako fetal dataset;34.8% LPC from Chen dataset; majorclass annotated by KRT5, high expression of KRT15

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual

Ontology Term: progenitor cellCL:0011026
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: unknown
CategoryClass of which the cell type is a subclass.: precursor cellCL:0011115
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: KRT15, KRT14, S100A2, CXCL14, RPLP1, MIR205HG, DST, AQP3, MT1X, SLC6A6
Canonical Marker Genes: KRT15
Rationale: 81.5% limbal progenitor cells+50.8% melanocytes from Lako adult dataset;9.1% corneal epithelium from Lako fetal dataset;34.8% LPC from Chen dataset; majorclass annotated by KRT5, high expression of KRT15

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual