Single Cell Atlas of Human Ocular Surface scRNA-seq: Cornea, Limbus, Sclera

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Cell Metadata

Fetal_Epi/LSC/LPC

Ontology Term: progenitor cellCL:0011026
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: precursor cellCL:0011115
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: PTPRD, NEDD4L, EXOC6B, KRT17, MT-ATP6, IGF2BP2, MT-CO3, DSC3, KMT2C, MT-CYB
Canonical Marker Genes: unknown
Rationale: majorclass annotated by KRT5; all from fetal multiome dataset from Chen lab; a relative-higher expression of MT-genes, not sure whether we should keep this cluster

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual

Ontology Term: progenitor cellCL:0011026
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: precursor cellCL:0011115
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: PTPRD, NEDD4L, EXOC6B, KRT17, MT-ATP6, IGF2BP2, MT-CO3, DSC3, KMT2C, MT-CYB
Canonical Marker Genes: unknown
Rationale: majorclass annotated by KRT5; all from fetal multiome dataset from Chen lab; a relative-higher expression of MT-genes, not sure whether we should keep this cluster

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual