Single Cell Atlas of Human Ocular Surface snRNA-seq: Cornea, Limbus, Sclera

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Cell Metadata

Epi-PMC

Ontology Term: epithelial cellCL:0000066
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: epitheliocyte
CategoryClass of which the cell type is a subclass.: eukaryotic cellCL:0000255
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: COL17A1, NKAIN2, MIR205HG, DST, IVNS1ABP, RASSF6, LAMA3, TENM2, MOXD1, SOX6
Canonical Marker Genes: unknown
Rationale: 95.3% K_Epi-Basal+21.3% K_Epi-TA from Sanes datasets; majorclass annotated by PAX6; from Epi-TAC, Epi-PMC, Epi-TDC/PMC, to Epi-TDC, KRT3 expression increases

Set of Labels Description: This atlas is an integrated collection of over 147k cells, derived from single-nuclei RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 26 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual

Ontology Term: epithelial cellCL:0000066
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: epitheliocyte
CategoryClass of which the cell type is a subclass.: eukaryotic cellCL:0000255
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: COL17A1, NKAIN2, MIR205HG, DST, IVNS1ABP, RASSF6, LAMA3, TENM2, MOXD1, SOX6
Canonical Marker Genes: unknown
Rationale: 95.3% K_Epi-Basal+21.3% K_Epi-TA from Sanes datasets; majorclass annotated by PAX6; from Epi-TAC, Epi-PMC, Epi-TDC/PMC, to Epi-TDC, KRT3 expression increases

Set of Labels Description: This atlas is an integrated collection of over 147k cells, derived from single-nuclei RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 26 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual