Human PBMC atlas - MonoDC2 cells

CD14_IFN2_CXCL10_CCL2

Full Name

IFN2 CXCL10/CCL2+ CD14-positive, CD16-negative classical monocyte

Closest Ontology Term

CD14-positive, CD16-negative classical monocyteCL:0002057

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

classical monocytes

Category

Class of which the cell type is a subclass.

CD14-positive, CD16-negative classical monocyteCL:0002057

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

Cluster expresses canonical classical monocyte markers and CXCL10/CCL2+ in addition to interferon sensing genes

Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

CXCL10, GBP4, LY6E, ISG15, IFI6, MX1, IFI44L, GBP5, IFIT1, IFIT2, IFIT3, RSAD2, ISG20, ZBP1, CCL2

Canonical Marker Genes

CD14

Rationale

Cluster expresses canonical classical monocyte markers and CXCL10/CCL2+ in addition to interferon sensing genes

Rationale DOI

https://doi.org/10.1038/s41590-020-0661-1

Inherited from Level_4

Set of Labels Description

Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.

Annotation Method

manual