Human PBMC atlas - MonoDC2 cells

CD14_IFN2_CXCL10_CCL2

Full Name: IFN2 CXCL10/CCL2+ CD14-positive, CD16-negative classical monocyte
Closest Ontology Term: CD14-positive, CD16-negative classical monocyteCL:0002057
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: classical monocytes
Category Class of which the cell type is a subclass.: CD14-positive, CD16-negative classical monocyteCL:0002057
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster expresses canonical classical monocyte markers and CXCL10/CCL2+ in addition to interferon sensing genes
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CXCL10, GBP4, LY6E, ISG15, IFI6, MX1, IFI44L, GBP5, IFIT1, IFIT2, IFIT3, RSAD2, ISG20, ZBP1, CCL2
Canonical Marker Genes: CD14
Rationale: Cluster expresses canonical classical monocyte markers and CXCL10/CCL2+ in addition to interferon sensing genes
Rationale DOI: https://doi.org/10.1038/s41590-020-0661-1

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual