Human PBMC atlas - MonoDC2 cells

CD14_IFN1_ALOX5AP

Full Name: IFN1 ALOX5AP+ CD14-positive, CD16-negative classical monocyte
Closest Ontology Term: CD14-positive, CD16-negative classical monocyteCL:0002057
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: classical monocytes
Category Class of which the cell type is a subclass.: CD14-positive, CD16-negative classical monocyteCL:0002057
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster expresses canonical classical monocyte markers and ALOX5AP+ in addition to interferon sensing genes
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ALOX5AP, CLU, LY6E, ISG15, RETN, MCEMP1, RSAD2, IFI44L, MX1, IFIT1, IFI6
Canonical Marker Genes: CD14
Rationale: Cluster expresses canonical classical monocyte markers and ALOX5AP+ in addition to interferon sensing genes
Rationale DOI: https://doi.org/10.1007/s12672-023-00826-9

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual