Human PBMC atlas - MonoDC2 cells

CD14_HLA-DQA1

Full Name: HLA-DQA1+ CD14-positive, CD16-negative classical monocyte
Closest Ontology Term: CD14-positive, CD16-negative classical monocyteCL:0002057
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: classical monocytes
Category Class of which the cell type is a subclass.: CD14-positive, CD16-negative classical monocyteCL:0002057
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster expresses canonical classical monocyte markers and HLA-DQA1+
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CD14, HLA-DQA1, C5AR1, HLA-DQA2, HLA-DRA, LMNA, ARL4C, CLEC10A, CD83, CXCL2, PID1, PRDM1
Canonical Marker Genes: CD14
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: Cluster expresses canonical classical monocyte markers and HLA-DQA1+
Rationale DOI: https://doi.org/10.1111/iji.12367

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual