Achilles tendon atlas - muscle cells

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Cell Metadata

Transitional skeletal muscle cells

Full Name: Transitional skeletal muscle cells
Closest Ontology Term: cell of skeletal muscleCL:0000188
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: skeletal muscle fiberCL:0008002
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MYBPC2, CPM, SORBS2, ATP2A2
Canonical Marker Genes: TRDN, TTN, NEB, DES, ACTN2
Rationale: This cell was annotated manually using canonical skeletal muscle cell markers in the field (TRDN, TTN, NEB, DES, ACTN2). These cells expressed markers of both fast and slow twitch markers (MYBPC2, CPM, SORBS2, ATP2A2) hence designated as "transitional"
Rationale DOI: https://doi.org/10.1096/fj.202300601RRR

Set of Labels Description: Lineage annotations were determined by Louvain clustering at resolution 0.1. Each lineage (fibroblast, muscle, immune, stromal) was then subsetted and reclustered. Final annotation resolution was chosen according to expression of biological markers; smaller clusters were combined were appropriate
Annotation Method: manual

Full Name: Transitional skeletal muscle cells
Closest Ontology Term: cell of skeletal muscleCL:0000188
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: skeletal muscle fiberCL:0008002
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MYBPC2, CPM, SORBS2, ATP2A2
Canonical Marker Genes: TRDN, TTN, NEB, DES, ACTN2
Rationale: This cell was annotated manually using canonical skeletal muscle cell markers in the field (TRDN, TTN, NEB, DES, ACTN2). These cells expressed markers of both fast and slow twitch markers (MYBPC2, CPM, SORBS2, ATP2A2) hence designated as "transitional"
Rationale DOI: https://doi.org/10.1096/fj.202300601RRR

Set of Labels Description: Lineage annotations were determined by Louvain clustering at resolution 0.1. Each lineage (fibroblast, muscle, immune, stromal) was then subsetted and reclustered. Final annotation resolution was chosen according to expression of biological markers; smaller clusters were combined were appropriate
Annotation Method: manual