• v6 Single cell atlas of the human retinal pigment epithelium and the choroid

Macrophages

Ontology Term

macrophageCL:0000235

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

histiocyte

Category

Class of which the cell type is a subclass.

mononuclear phagocyteCL:0000113

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

—

Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

MRC1, CD163

Canonical Marker Genes

MRC1, CD163

Negative Marker Genes

Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.

—

Rationale

Cell identities were assigned via label transfer using the CellTypist 'Immune_All_High/Low' models.

Inherited from author_cell_type

Set of Labels Description

This dataset provides high-resolution annotations and sub-clustering of immune cells from the human retinal pigment epithelium (RPE)/choroid complex—a tissue essential for the survival and function of the neural retina. By analyzing 101,471 nuclei across 53 donors, we resolved 20 choroidal immune cell types/states.

Annotation Method

manual