- Full Name
- mucosal invariant T cell /TRDV2+ gamma-delta T cell
- Closest Ontology Term
- mucosal invariant T cellCL:0000940
- SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.
- mucosal invariant T-cell / TRDV2+ gamma-delta T cells, mucosal invariant T lymphocyte / TRDV2+ gamma-delta T cells, mucosal invariant T-lymphocyte / TRDV2+ gamma-delta T cells
- CategoryClass of which the cell type is a subclass.
- T cellCL:0000084
- Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.
- KLRB1, TRDC, TRGC1, TRGC2, IL18RAP, CEBPD, ZBTB16, RORA, CCR6, IL23R
- Canonical Marker Genes
- KLRB1, TRDC, TRGC1, TRGC2, IL18RAP, CEBPD, ZBTB16, RORA, CCR6, IL23R
- Rationale
- This cluster is a mix of MAIT cells (KLRB1, SLC4A10, ZBTB16, IL23R, IL18R1, CEPBD, CCR6, DPP4) and Vδ2Vγ9+ γδ T cells (TRDV2, TRDC, TRGC1, TRGC2, ZBTB16, KLRB1, IL18R1, DPP4) which share a similar phenotype and transcriptional profile (Provine et al., 2018; Wragg et al., 2020).