snRNA-seq of human retina - retinal ganglion cell subset

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Cell Metadata

HRGC10

Ontology Term: retinal ganglion cellCL:0000740
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: RGC, ganglion cell of retina, RGCs, gangliocyte
Category Class of which the cell type is a subclass.: retinal cellCL:0009004
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: EYS, HMGN1, SLC6A6, TCF4, DISC1, PLCD4, SAG, PDE6A, PTPN13, THSD7B, NCKAP5
Canonical Marker Genes: unknown
Rationale: 56.7%Unassigned+24.5%MG-ON+16.3%MG-OFF of the Sanes dataset; 96.7%Unassigned of the Shekhar dataset; 98.8%RGC6 of the macaque dataset; 47.6%Unassigned+28.2%13_Novel+18.0%6_W3B of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: A total of 11 retinal ganglion cell clusters were identified from over 399K retinal ganglion cell nuclei in the current atlas. Utilizing previously characterized markers from macaque, 5 clusters can be annotated.
Annotation Method: manual

Ontology Term: retinal ganglion cellCL:0000740
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: RGC, ganglion cell of retina, RGCs, gangliocyte
Category Class of which the cell type is a subclass.: retinal cellCL:0009004
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: EYS, HMGN1, SLC6A6, TCF4, DISC1, PLCD4, SAG, PDE6A, PTPN13, THSD7B, NCKAP5
Canonical Marker Genes: unknown
Rationale: 56.7%Unassigned+24.5%MG-ON+16.3%MG-OFF of the Sanes dataset; 96.7%Unassigned of the Shekhar dataset; 98.8%RGC6 of the macaque dataset; 47.6%Unassigned+28.2%13_Novel+18.0%6_W3B of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: A total of 11 retinal ganglion cell clusters were identified from over 399K retinal ganglion cell nuclei in the current atlas. Utilizing previously characterized markers from macaque, 5 clusters can be annotated.
Annotation Method: manual