snRNA-seq of human retina - amacrine cell subset

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Cell Metadata

HAC45

Ontology Term: GABAergic amacrine cellCL:4030027
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: amacrine cell, GABAergic
CategoryClass of which the cell type is a subclass.: amacrine cellCL:0000561
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: CYP2E1, SDK2, ST8SIA4, LGR5, MYO16, MOB3B, DOCK2, CSGALNACT1, INSYN2B, TNR
Canonical Marker Genes: unknown
Rationale: 49.5%Gaba11+46.6%Unassigned of the Sanes dataset; 99.6%Ga3 of the macaque dataset; 99.2%AC29 of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: Over 89 amacrine cell types were identified among over 571K amacrine nuclei in the current atlas. These 89 cell types can be categorized into GABAergic amacrine cells, Glycinergic amacrine cells, and Both type using marker genes, specifically the GABA-synthetic enzymes GAD1 and GAD2, and the glycine transporter SLC6A9. Based on previously characterized markers, 14 of the 89 amacrine cell clusters could be annotated as known amacrine types.
Annotation Method: manual

Ontology Term: GABAergic amacrine cellCL:4030027
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: amacrine cell, GABAergic
CategoryClass of which the cell type is a subclass.: amacrine cellCL:0000561
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: CYP2E1, SDK2, ST8SIA4, LGR5, MYO16, MOB3B, DOCK2, CSGALNACT1, INSYN2B, TNR
Canonical Marker Genes: unknown
Rationale: 49.5%Gaba11+46.6%Unassigned of the Sanes dataset; 99.6%Ga3 of the macaque dataset; 99.2%AC29 of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: Over 89 amacrine cell types were identified among over 571K amacrine nuclei in the current atlas. These 89 cell types can be categorized into GABAergic amacrine cells, Glycinergic amacrine cells, and Both type using marker genes, specifically the GABA-synthetic enzymes GAD1 and GAD2, and the glycine transporter SLC6A9. Based on previously characterized markers, 14 of the 89 amacrine cell clusters could be annotated as known amacrine types.
Annotation Method: manual