Cell Annotation
Platform

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snRNA-seq of human retina - retinal ganglion cell subset

Main

Cell Metadata

Ontology Term: retinal ganglion cellCL:0000740
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: RGC, ganglion cell of retina, RGCs, gangliocyte
Category Class of which the cell type is a subclass.: retinal cellCL:0009004
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ZPBP, DPP10-AS3, HES1, AC008067.1
Canonical Marker Genes: unknown
Rationale: 76.2%MG-OFF+14.7%Unassigned of the Sanes dataset; 46.4%MG_OFF+27.2%Unassigned+26.5%MG_ON of the Shekhar dataset; 85.4%Unassigned of the macaque dataset; 45.1%Unassigned+31.4%4_FminiOFF+11.2%15_Novel of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: A total of 11 retinal ganglion cell clusters were identified from over 399K retinal ganglion cell nuclei in the current atlas. Utilizing previously characterized markers from macaque, 5 clusters can be annotated.
Annotation Method: manual