snRNA-seq of human retina - amacrine cell subset

Main

Cell Metadata

HAC65

Ontology Term: amacrine cellCL:0000561
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: ACs, AC, amacrine neuron
CategoryClass of which the cell type is a subclass.: GABAergic Glycinergic amacrine cells
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: SDC2, AGBL1, CLNK, AL136456.1, AC064875.1, FOXP2, NRP2, KCNH1, CDH6, ADAMTS9-AS2
Canonical Marker Genes: unknown
Rationale: 98.7%Gaba10 of the Sanes dataset; 99.2%Unassigned of the macaque dataset; 97.5%AC20 of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: Over 89 amacrine cell types were identified among over 571K amacrine nuclei in the current atlas. These 89 cell types can be categorized into GABAergic amacrine cells, Glycinergic amacrine cells, and Both type using marker genes, specifically the GABA-synthetic enzymes GAD1 and GAD2, and the glycine transporter SLC6A9. Based on previously characterized markers, 14 of the 89 amacrine cell clusters could be annotated as known amacrine types.
Annotation Method: manual

Ontology Term: amacrine cellCL:0000561
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: ACs, AC, amacrine neuron
CategoryClass of which the cell type is a subclass.: GABAergic Glycinergic amacrine cells
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: SDC2, AGBL1, CLNK, AL136456.1, AC064875.1, FOXP2, NRP2, KCNH1, CDH6, ADAMTS9-AS2
Canonical Marker Genes: unknown
Rationale: 98.7%Gaba10 of the Sanes dataset; 99.2%Unassigned of the macaque dataset; 97.5%AC20 of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: Over 89 amacrine cell types were identified among over 571K amacrine nuclei in the current atlas. These 89 cell types can be categorized into GABAergic amacrine cells, Glycinergic amacrine cells, and Both type using marker genes, specifically the GABA-synthetic enzymes GAD1 and GAD2, and the glycine transporter SLC6A9. Based on previously characterized markers, 14 of the 89 amacrine cell clusters could be annotated as known amacrine types.
Annotation Method: manual