Single cell atlas of the human trabecular meshwork and ciliary body - snRNA-seq

Main

Cell Metadata

Vascular_Endothelium

Ontology Term: blood vessel endothelial cellCL:0000071
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: unknown
CategoryClass of which the cell type is a subclass.: endothelial cell of vascular treeCL:0002139
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: ALPL, BTNL9, CP, SLC2A1
Canonical Marker Genes: BTNL9
Rationale: This Vascular Endothelium sub-class is annotated by the marker BTNL9 .

Set of Labels Description: This cell annotation set focuses on the trabecular meshwork (TM) and ciliary body (CB), key tissues regulating aqueous humor dynamics and intraocular pressure in the human eye. Using single-nucleus RNA-seq, we analyzed over 1 million cells from 70 healthy donors, identifying 9 major cell classes and 18 sub-classes. As part of the Human Cell Atlas initiative, this dataset integrates transcriptomic and chromatin accessibility data and is publicly accessible via CELLxGENE and the UCSC Cell Browser, offering a valuable resource for understanding ocular physiology and disease mechanisms.
Annotation Method: manual

Main

Cell Metadata

Ontology Term: blood vessel endothelial cellCL:0000071
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: unknown
CategoryClass of which the cell type is a subclass.: endothelial cell of vascular treeCL:0002139
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: ALPL, BTNL9, CP, SLC2A1
Canonical Marker Genes: BTNL9
Rationale: This Vascular Endothelium sub-class is annotated by the marker BTNL9 .

Set of Labels Description: This cell annotation set focuses on the trabecular meshwork (TM) and ciliary body (CB), key tissues regulating aqueous humor dynamics and intraocular pressure in the human eye. Using single-nucleus RNA-seq, we analyzed over 1 million cells from 70 healthy donors, identifying 9 major cell classes and 18 sub-classes. As part of the Human Cell Atlas initiative, this dataset integrates transcriptomic and chromatin accessibility data and is publicly accessible via CELLxGENE and the UCSC Cell Browser, offering a valuable resource for understanding ocular physiology and disease mechanisms.
Annotation Method: manual