Single Cell Atlas of Human Ocular Surface scRNA-seq: Cornea, Limbus, Sclera

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Cell Metadata

Schwann_N

Ontology Term: non-myelinating Schwann cellCL:0002376
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: Schwann cell
Category Class of which the cell type is a subclass.: Schwann cellCL:0002573
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CDH19, NRXN1, STARD13, SORCS1, ADGRB3, GPM6B, CADM2, NCAM2, SCN7A, DST
Canonical Marker Genes: SCN7A, NRXN1
Rationale: 86.7% ScC from Shi dataset; 89.5% corneal endothelium from Lako adult dataset; 20.7% corneal endothelium + 79.7% corneal nerves from Lako fetal dataset; celltype annotated by SCN7A, NRXN1

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual

Ontology Term: non-myelinating Schwann cellCL:0002376
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: Schwann cell
Category Class of which the cell type is a subclass.: Schwann cellCL:0002573
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CDH19, NRXN1, STARD13, SORCS1, ADGRB3, GPM6B, CADM2, NCAM2, SCN7A, DST
Canonical Marker Genes: SCN7A, NRXN1
Rationale: 86.7% ScC from Shi dataset; 89.5% corneal endothelium from Lako adult dataset; 20.7% corneal endothelium + 79.7% corneal nerves from Lako fetal dataset; celltype annotated by SCN7A, NRXN1

Set of Labels Description: This atlas is an integrated collection of over 815k cells, derived from single-cell RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 31 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual