Single Cell Atlas of Human Ocular Surface snRNA-seq: Cornea, Limbus, Sclera

Corneal Stromal Keratocytes

Ontology Term

keratocyteCL:0002363

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

corneal fibroblast, corneal keratocyte

Category

Class of which the cell type is a subclass.

neural crest derived fibroblastCL:0000005

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

ITGBL1, COL6A3, DCN, BICC1, COL12A1, ABCA6, MME, CEMIP, COL5A2, PTPRG

Canonical Marker Genes

ALDH3A1, MME, DCN

Rationale

50% FibroX+95.5% K_Fibro+74.3% TM_Fibro from Sanes datasets; majorclass annotated by DCN, celltype annotated by ALDH3A1, MME

Inherited from author_cell_type

Set of Labels Description

This atlas is an integrated collection of over 147k cells, derived from single-nuclei RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 26 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.

Annotation Method

manual