Single Cell Atlas of Human Ocular Surface snRNA-seq: Cornea, Limbus, Sclera

Main

Cell Metadata

CC_VenEndo

Ontology Term: endothelial cellCL:0000115
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: endotheliocyte
CategoryClass of which the cell type is a subclass.: lining cellCL:0000213
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: LDB2, PECAM1, TSHZ2, MCTP1, ZNF385D, ELMO1, DOCK4, TGFBR2, ADGRL4, EMCN
Canonical Marker Genes: PECAM1, VWF, COL15A1
Rationale: 98.2% CC_VenEndo+18% VascEndo from Sanes datasets; majorclass annotated by PECAM1, celltype annotated by COL15A1

Set of Labels Description: This atlas is an integrated collection of over 147k cells, derived from single-nuclei RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 26 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual

Main

Cell Metadata

Ontology Term: endothelial cellCL:0000115
SynonymsTerms that have the same, or nearly the same, meaning as the selected cell type.: endotheliocyte
CategoryClass of which the cell type is a subclass.: lining cellCL:0000213
Marker Gene EvidenceGene markers used by researcher to assign this cell annotation.: LDB2, PECAM1, TSHZ2, MCTP1, ZNF385D, ELMO1, DOCK4, TGFBR2, ADGRL4, EMCN
Canonical Marker Genes: PECAM1, VWF, COL15A1
Rationale: 98.2% CC_VenEndo+18% VascEndo from Sanes datasets; majorclass annotated by PECAM1, celltype annotated by COL15A1

Set of Labels Description: This atlas is an integrated collection of over 147k cells, derived from single-nuclei RNA-seq data of human ocular surface, including cornea, limbus, and anterior sclera. These cells have been categorized into 10 major cell classes and 26 types. This is the initial cell type label for the atlas annotation. These labels will be examined, refined, and updated during the annotation jamboree.
Annotation Method: manual