Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.
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Rationale
LOCATION:
Adjacent to epidermis.
GENE EXPRESSION:
Superficial dermal collagens (COL18, COL23) and WNT inhibitors (WIF1, RSPO1).
SKIN-SPECIFIC:
Papillary fibroblasts.
CROSS-TISSUE INSIGHTS:
Variable across tissues, which may reflect a role in imprinting epithelial identity. Highest similarity to nasal mucosa epithelia, which may reflect increased similarity of nasal mucosa epithelia to skin relative to other tissues.
Inherited from cell_type
Set of Labels Description
Aim to harmonise skin fibroblast labels across studies in both health and disease. This specific dataset includes only healthy/non-lesional cells.
