Cell Annotation
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Skin fibroblasts - Pan-disease fibroblast atlas in skin fibrosis, inflammation, and cancer

Main

Cell Metadata

Full Name: Fascial fibroblast
Closest Ontology Term: skin fibroblastCL:0002620
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: skin fibroblastCL:0002620
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ITGA10, CCN3, DPP4, CDH13, PRG4, CRTAC1, PCOLCE2, LGR5
Canonical Marker Genes: unknown
Rationale: Fascial fibroblasts were obtained from Dupuytren's contracture datasets (non-lesional fascia was obtained in these studies). Fascial fibroblasts expressed many F2: Universal markers, in addition to unique marker genes such as ITGA10 and the known fascial marker CCN3 (NOV3) ((Correa-Gallegos et al. 2019)
Rationale DOI: 10.1038/s41586-019-1794-y

Set of Labels Description: Aim to harmonise skin fibroblast labels across studies in both health and disease.
Annotation Method: manual