Cell Annotation
Platform

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snRNA-seq of human optic nerve and optic nerve head - all cells

Main

Cell Metadata

Ontology Term: oligodendrocyteCL:0000128
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: oligodendrocyte SVEP1+
Category Class of which the cell type is a subclass.: myelinating glial cellCL:4023154
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ST18, MOG, MOBP, RBFOX1, SVEP1
Canonical Marker Genes: MOG, MOBP, SVEP1
Rationale: An oligodendrocyte sub class that expresses ST18 and SVEP1
Rationale DOI: https://doi.org/10.1016/j.neuron.2022.03.008

Set of Labels Description: We used scVI for data integration and then manually annotated each cell cluster based on marker gene expression
Annotation Method: both
Algorithm Name: scVI
Algorithm Version: scvi-tools 1.3.0
Algorithm URL: https://github.com/scverse/scvi-tools