Cell Annotation
Platform

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snRNA-seq of human optic nerve and optic nerve head - fibroblasts

Main

Cell Metadata

Ontology Term: fibroblastCL:0000057
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: Fibrolast x cell
Category Class of which the cell type is a subclass.: stromal cellCL:0000499
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: EBF2, SLC22A3, DCN
Canonical Marker Genes: EBF2, SLC22A3, DCN
Rationale: A fibroblast sub cluster that expresses EBF2 and SLC22A3
Rationale DOI: https://doi.org/10.1073/pnas.2306153120

Set of Labels Description: We used scVI for data integration and then manually annotated each cell cluster with scanpy based on marker gene expression
Annotation Method: both
Algorithm Name: scVI
Algorithm Version: scvi-tools 1.3.0
Algorithm URL: https://github.com/scverse/scvi-tools