HCA Gut Cell Atlas v1 Myeloid Lineage

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Cell Metadata

DC cDC2

Ontology Term: CD11b-positive dendritic cellCL:0002465
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: cDC2
Category Class of which the cell type is a subclass.: dendritic cellCL:0000451
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CD1C, TCTN3, FCER1A, CLEC10A, SPI1, SIRPA
Canonical Marker Genes: CD1C, FCER1A, CLEC10A
Rationale: CD1C, CLEC10A, FCER1A, SIRPA, define antigen presenting type 2 conventional dendritic cells with CD11b positive identity and non crosspresenting functions
Rationale DOI: 10.1126/science.aah4573; 10.1016/j.cell.2019.06.029

Set of Labels Description: Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering
Annotation Method: both
Algorithm Name: scVI
Algorithm Version: 1.3.2
Algorithm URL: https://github.com/scverse/scvi-tools

Ontology Term: CD11b-positive dendritic cellCL:0002465
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: cDC2
Category Class of which the cell type is a subclass.: dendritic cellCL:0000451
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CD1C, TCTN3, FCER1A, CLEC10A, SPI1, SIRPA
Canonical Marker Genes: CD1C, FCER1A, CLEC10A
Rationale: CD1C, CLEC10A, FCER1A, SIRPA, define antigen presenting type 2 conventional dendritic cells with CD11b positive identity and non crosspresenting functions
Rationale DOI: 10.1126/science.aah4573; 10.1016/j.cell.2019.06.029

Set of Labels Description: Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering
Annotation Method: both
Algorithm Name: scVI
Algorithm Version: 1.3.2
Algorithm URL: https://github.com/scverse/scvi-tools