HCA Gut Cell Atlas v1 Lymphoid Lineage

B Naive

Ontology Term

naive B cellCL:0000788

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

naive B cell

Category

Class of which the cell type is a subclass.

B cellCL:0000236

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

IGHM, IGHD

Canonical Marker Genes

IGHM, IGHD, TCL1A

Negative Marker Genes

Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.

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Rationale

MARCKSL1 and IGHD were found in some subclusters found near other follicular B cells. These have high HLA genes, CD79A and B

Inherited from Prelim annotation

Set of Labels Description

Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering

Annotation Method

both

Algorithm Name

scVI

Algorithm Version

1.3.2

Algorithm URL

https://github.com/scverse/scvi-tools