Human Gut Cell Atlas (HGCA) v1 - All Cells

CD8 Effector/Memory

Ontology Term

effector memory CD8-positive, alpha-beta T cell, terminally differentiatedCL:0001062

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

effector memory CD8 T cell, Teff/mem

Category

Class of which the cell type is a subclass.

CD8-positive, alpha-beta T cellCL:0000625

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

IL2, GZMA, GZMK, GZMB, KLRG1

Canonical Marker Genes

GZMB, PRF1, KLRG1

Rationale

No CX3CR1 but IL2, granzymes, and CD8 signatures are found abundantly in single cell data of the gut

Inherited from hgca_celltype_v0

Set of Labels Description

Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering

Annotation Method

both

Algorithm Name

scVI

Algorithm Version

1.3.2

Algorithm URL

https://github.com/scverse/scvi-tools