Human Adipose Tissue Atlas v1.0 — Vascular cells

Main

Cell Metadata

ECs

Ontology Term: endothelial cellCL:0000115
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: vascular endothelial cell
Category Class of which the cell type is a subclass.: endothelial cellCL:0000115
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: PECAM1, CDH5, MECOM, ENPEP
Canonical Marker Genes: PECAM1, CDH5, MECOM, ENPEP
Rationale: PECAM1 (CD31) and CDH5 (VE-cadherin) are pan-endothelial markers present across all endothelial subtypes. MECOM and ENPEP further confirm endothelial identity. Together these markers define the endothelial cell compartment encompassing capillary, arterial, venous, and lymphatic EC subtypes.
Rationale DOI: 10.1038/s42255-025-01296-9

Set of Labels Description: Level 2 cell type labels (represents broad clusters most studies tend to identify).
Annotation Method: manual

Main

Cell Metadata

Ontology Term: endothelial cellCL:0000115
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: vascular endothelial cell
Category Class of which the cell type is a subclass.: endothelial cellCL:0000115
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: PECAM1, CDH5, MECOM, ENPEP
Canonical Marker Genes: PECAM1, CDH5, MECOM, ENPEP
Rationale: PECAM1 (CD31) and CDH5 (VE-cadherin) are pan-endothelial markers present across all endothelial subtypes. MECOM and ENPEP further confirm endothelial identity. Together these markers define the endothelial cell compartment encompassing capillary, arterial, venous, and lymphatic EC subtypes.
Rationale DOI: 10.1038/s42255-025-01296-9

Set of Labels Description: Level 2 cell type labels (represents broad clusters most studies tend to identify).
Annotation Method: manual