Human Adipose Tissue Atlas v1.0 — Vascular cells

Main

Cell Metadata

Mural cells

Ontology Term: mural cellCL:0008034
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: mural cellCL:0008034
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: STEAP4, COL25A1, MYOCD, MYH11
Canonical Marker Genes: STEAP4, COL25A1, MYOCD, MYH11
Rationale: STEAP4 and COL25A1 show enriched expression in pericytes in adipose tissue single-cell datasets. MYOCD (myocardin) and MYH11 (smooth muscle myosin heavy chain) identify smooth muscle cells. Together these markers define the mural cell compartment encompassing pericytes and smooth muscle cells.
Rationale DOI: 10.1038/s42255-025-01296-9

Set of Labels Description: Level 2 cell type labels (represents broad clusters most studies tend to identify).
Annotation Method: manual

Ontology Term: mural cellCL:0008034
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: mural cellCL:0008034
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: STEAP4, COL25A1, MYOCD, MYH11
Canonical Marker Genes: STEAP4, COL25A1, MYOCD, MYH11
Rationale: STEAP4 and COL25A1 show enriched expression in pericytes in adipose tissue single-cell datasets. MYOCD (myocardin) and MYH11 (smooth muscle myosin heavy chain) identify smooth muscle cells. Together these markers define the mural cell compartment encompassing pericytes and smooth muscle cells.
Rationale DOI: 10.1038/s42255-025-01296-9

Set of Labels Description: Level 2 cell type labels (represents broad clusters most studies tend to identify).
Annotation Method: manual