Human Adipose Tissue Atlas v1.0 — Mesothelial cells

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Cell Metadata

Mesothelial cells

Ontology Term: mesothelial cellCL:0000077
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: mesotheliocyte
Category Class of which the cell type is a subclass.: meso-epithelial cellCL:0002078
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MSLN, KRT19, BNC1
Canonical Marker Genes: MSLN, KRT19, BNC1
Rationale: MSLN (mesothelin) is a glycoprotein highly expressed on the surface of mesothelial cells lining serous cavities. KRT19 (cytokeratin 19) is an epithelial intermediate filament protein characteristic of mesothelial and epithelial lineages. BNC1 (basonuclin-1) marks mesothelial identity and distinguishes these cells from endothelial and stromal populations. Together, these markers reliably identify mesothelial cells in adipose tissue.
Rationale DOI: 10.1038/s42255-025-01296-9

Ontology Term: mesothelial cellCL:0000077
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: mesotheliocyte
Category Class of which the cell type is a subclass.: meso-epithelial cellCL:0002078
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MSLN, KRT19, BNC1
Canonical Marker Genes: MSLN, KRT19, BNC1
Rationale: MSLN (mesothelin) is a glycoprotein highly expressed on the surface of mesothelial cells lining serous cavities. KRT19 (cytokeratin 19) is an epithelial intermediate filament protein characteristic of mesothelial and epithelial lineages. BNC1 (basonuclin-1) marks mesothelial identity and distinguishes these cells from endothelial and stromal populations. Together, these markers reliably identify mesothelial cells in adipose tissue.
Rationale DOI: 10.1038/s42255-025-01296-9