Human Adipose Tissue Atlas v1.0 — ASPCs

DPP4⁺ ASPCs

Ontology Term

fibro/adipogenic progenitor cellCL:0009099

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

mesenchymal stem cell of adipose tissue, preadipocyte

Category

Class of which the cell type is a subclass.

progenitor cellCL:0011026

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

PDGFRA, DCN, DPP4, CD55, PI16

Canonical Marker Genes

PDGFRA, DCN, DPP4, CD55, PI16

Rationale

PDGFRA and DCN (decorin) are general ASPC/stromal markers broadly expressed across adipose stromal and progenitor cell populations. DPP4 (dipeptidyl peptidase 4), CD55 (decay accelerating factor), and PI16 (peptidase inhibitor 16) show enriched expression in this specific subpopulation, together distinguishing DPP4⁺ ASPCs from other ASPC subtypes. Together these markers identify a distinct ASPC subpopulation within the broader stromal compartment.

Rationale DOI

10.1038/s42255-025-01296-9

Inherited from lvl3_cell_types

Set of Labels Description

Level 3 cell type labels (most fine-grained).

Annotation Method

manual