IGFBP2⁺ ASPCs
Ontology Term
- fibro/adipogenic progenitor cellCL:0009099
Synonyms
Terms that have the same, or nearly the same, meaning as the selected cell type.- mesenchymal stem cell of adipose tissue, preadipocyte
Category
Class of which the cell type is a subclass.- progenitor cellCL:0011026
Ontology Assessment
Disagreements with any aspect of the Cell Ontology.- —
Marker Gene Evidence
Gene markers used by researcher to assign this cell annotation.- PDGFRA, DCN, IGFBP2
Rationale
- PDGFRA and DCN (decorin) are general ASPC/stromal markers broadly expressed across adipose stromal and progenitor cell populations. IGFBP2 (insulin-like growth factor binding protein 2) shows enriched expression in this specific subpopulation and marks a depot-restricted population found exclusively in visceral adipose tissue (AVAT), distinguishing IGFBP2⁺ ASPCs from other ASPC subtypes present across depots. Together these markers identify a visceral-specific ASPC subpopulation within the broader stromal compartment.
Inherited from lvl3_cell_types
- Set of Labels Description
- Level 3 cell type labels (most fine-grained).
- Annotation Method
- manual
