Human Adipose Tissue Atlas v1.0 — Abdominal Visceral WAT

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Cell Metadata

CD8⁺ T cells

Ontology Term: CD8-positive, alpha-beta T cellCL:0000625
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: CD8-positive, alpha-beta T-lymphocyte, alpha-beta T lymphocyte, alpha-beta T-cell
Category Class of which the cell type is a subclass.: T cellCL:0000084
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CD3D, CD3E, CD8A
Canonical Marker Genes: CD3D, CD3E, CD8A
Rationale: CD3D and CD3E are components of the T cell receptor signaling complex, confirming T cell lineage identity. CD8A is a surface co-receptor defining the CD8⁺ T cell lineage and distinguishing these cells from CD4⁺ T cells. Together these markers reliably identify CD8⁺ T cells within the T cell compartment.
Rationale DOI: 10.57785/e9e1-wh09 10.1038/s42255-025-01296-9

Ontology Term: CD8-positive, alpha-beta T cellCL:0000625
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: CD8-positive, alpha-beta T-lymphocyte, alpha-beta T lymphocyte, alpha-beta T-cell
Category Class of which the cell type is a subclass.: T cellCL:0000084
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CD3D, CD3E, CD8A
Canonical Marker Genes: CD3D, CD3E, CD8A
Rationale: CD3D and CD3E are components of the T cell receptor signaling complex, confirming T cell lineage identity. CD8A is a surface co-receptor defining the CD8⁺ T cell lineage and distinguishing these cells from CD4⁺ T cells. Together these markers reliably identify CD8⁺ T cells within the T cell compartment.
Rationale DOI: 10.57785/e9e1-wh09 10.1038/s42255-025-01296-9