Human Adipose Tissue Atlas v1.0 — Lymphoid cells

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Cell Metadata

B cells

Ontology Term: B cellCL:0000236
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: B lymphocyte, B-lymphocyte, B-cell
Category Class of which the cell type is a subclass.: lymphocyteCL:0000542
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MS4A1, CD79A, IGKC
Canonical Marker Genes: MS4A1, CD79A, IGKC
Rationale: MS4A1 (CD20) is a surface marker broadly expressed on mature B cells. CD79A is a component of the B cell receptor signaling complex and confirms B cell lineage identity. IGKC (immunoglobulin kappa constant) reflects active immunoglobulin expression characteristic of B cells. Together these markers reliably identify B cells and distinguish them from other lymphoid populations.
Rationale DOI: 10.1038/s42255-025-01296-9

Ontology Term: B cellCL:0000236
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: B lymphocyte, B-lymphocyte, B-cell
Category Class of which the cell type is a subclass.: lymphocyteCL:0000542
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MS4A1, CD79A, IGKC
Canonical Marker Genes: MS4A1, CD79A, IGKC
Rationale: MS4A1 (CD20) is a surface marker broadly expressed on mature B cells. CD79A is a component of the B cell receptor signaling complex and confirms B cell lineage identity. IGKC (immunoglobulin kappa constant) reflects active immunoglobulin expression characteristic of B cells. Together these markers reliably identify B cells and distinguish them from other lymphoid populations.
Rationale DOI: 10.1038/s42255-025-01296-9