Human Adipose Tissue Atlas v1.0 — Lymphoid cells

Main

Cell Metadata

ILC3

Ontology Term: group 3 innate lymphoid cellCL:0001071
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: ILC3
Category Class of which the cell type is a subclass.: lymphocyteCL:0000542
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: IL7R, CD200R1
Canonical Marker Genes: IL7R, CD200R1
Rationale: IL7R (CD127) is broadly expressed on innate lymphoid cells and confirms ILC lineage identity. CD200R1 shows enriched expression in ILC3s and has been reported as a marker of this population in the literature. Together these markers identify ILC3s within the innate lymphoid cell compartment and distinguish them from other ILC subsets and conventional T cells.
Rationale DOI: 10.1038/s42255-025-01296-9

Ontology Term: group 3 innate lymphoid cellCL:0001071
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: ILC3
Category Class of which the cell type is a subclass.: lymphocyteCL:0000542
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: IL7R, CD200R1
Canonical Marker Genes: IL7R, CD200R1
Rationale: IL7R (CD127) is broadly expressed on innate lymphoid cells and confirms ILC lineage identity. CD200R1 shows enriched expression in ILC3s and has been reported as a marker of this population in the literature. Together these markers identify ILC3s within the innate lymphoid cell compartment and distinguish them from other ILC subsets and conventional T cells.
Rationale DOI: 10.1038/s42255-025-01296-9