Human Adipose Tissue Atlas v1.0 — Myeloid cells

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Cell Metadata

Proliferating macrophages

Ontology Term: cycling macrophageCL:4033076
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: proliferating macrophage
Category Class of which the cell type is a subclass.: macrophageCL:0000235
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MRC1, MKI67
Canonical Marker Genes: MRC1, MKI67
Rationale: MRC1 (CD206) is a general macrophage marker confirming macrophage identity. MKI67 (Ki-67) is a marker of active cell proliferation. Together these markers identify a proliferating macrophage population rather than a transcriptionally distinct macrophage subset.
Rationale DOI: 10.1038/s42255-025-01296-9 10.1016/j.celrep.2018.06.110

Ontology Term: cycling macrophageCL:4033076
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: proliferating macrophage
Category Class of which the cell type is a subclass.: macrophageCL:0000235
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MRC1, MKI67
Canonical Marker Genes: MRC1, MKI67
Rationale: MRC1 (CD206) is a general macrophage marker confirming macrophage identity. MKI67 (Ki-67) is a marker of active cell proliferation. Together these markers identify a proliferating macrophage population rather than a transcriptionally distinct macrophage subset.
Rationale DOI: 10.1038/s42255-025-01296-9 10.1016/j.celrep.2018.06.110