Human Adipose Tissue Atlas v1.0 — Myeloid cells

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Cell Metadata

Macrophages & Monocytes

Ontology Term: myeloid leukocyteCL:0000766
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: myeloid leukocyteCL:0000766
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MRC1, F13A1, FCN1
Canonical Marker Genes: MRC1, F13A1, FCN1
Rationale: MRC1 (CD206) and F13A1 are broadly expressed across tissue-resident macrophage populations, while FCN1 (ficolin-1) shows enriched expression in monocyte populations. Together these markers define the macrophage and monocyte compartment encompassing LAMs, PVMs, inflammatory macrophages, proliferating macrophages, classical monocytes, non-classical monocytes, and CD14⁺S100A8/9⁺ monocytes.
Rationale DOI: 10.1038/s42255-025-01296-9

Set of Labels Description: Level 2 cell type labels (represents broad clusters most studies tend to identify).
Annotation Method: manual

Ontology Term: myeloid leukocyteCL:0000766
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: myeloid leukocyteCL:0000766
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MRC1, F13A1, FCN1
Canonical Marker Genes: MRC1, F13A1, FCN1
Rationale: MRC1 (CD206) and F13A1 are broadly expressed across tissue-resident macrophage populations, while FCN1 (ficolin-1) shows enriched expression in monocyte populations. Together these markers define the macrophage and monocyte compartment encompassing LAMs, PVMs, inflammatory macrophages, proliferating macrophages, classical monocytes, non-classical monocytes, and CD14⁺S100A8/9⁺ monocytes.
Rationale DOI: 10.1038/s42255-025-01296-9

Set of Labels Description: Level 2 cell type labels (represents broad clusters most studies tend to identify).
Annotation Method: manual