Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.
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Rationale
MS4A1 (CD20) and CD79A confirm B cell lineage identity, with IGKC reflecting active immunoglobulin expression. JCHAIN and MZB1 mark antibody-secreting plasma cells, which are included in this compartment as terminally differentiated B cell-derived populations. Together these markers define the B cell compartment encompassing naive B cells and plasma cells.
