Human PBMC atlas - DC_DC2 cells

pDC_IFN

Full Name: IFN plasmacytoid dendritic cell
Closest Ontology Term: plasmacytoid dendritic cellCL:0000784
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: plasmacytoid dendritic cellCL:0000784
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster with canonical pDC markers in addition to interferon sensing genes
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: LY6E, IFI6, ISG15, MX1, IFI44L
Canonical Marker Genes: IL3RA, TCF4, IRF7, IRF8, JCHAIN, LILRA4
Rationale: Cluster with canonical pDC markers in addition to interferon sensing genes
Rationale DOI: https://doi.org/10.1126/science.aah4573 https://doi.org/10.1016/j.cytogfr.2007.10.006 https://doi.org/10.1126/science.aag3009

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual