Human PBMC atlas - DC_DC2 cells

Summary

Metadata

Dataset Type

Integrated. The file includes an integrated collection of datasets.

Total Cells

145,941

organism

Homo sapiens

tissue

blood

assay

10x 5' v2 (57,926 cells)10x 5' v1 (41,520 cells)10x 3' v2 (27,223 cells)10x 3' v3 (19,272 cells)

disease

normal (64,987 cells)COVID-19 (61,424 cells)systemic lupus erythematosus (12,200 cells)respiratory system disorder (3,731 cells)infectious disease with sepsis (1,421 cells)post-COVID-19 disorder (1,297 cells)bacterial pneumonia (546 cells)influenza (317 cells)viral pneumonia (18 cells)

Cell Labels

Level_4

Description

Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.

Annotation Method

manual

Cell Labels (21)

Cells (145,941)

DC3_CD14_CLEC4E

33,061

DC2

18,246

DC2_CD83_KLF4_CXCR4

17,379

pDC1

11,678

DC3_G0S2_KLF4_CD83

10,531

DC2_IFN

8,371

DC3_IFN

6,390

pDC2_FCRLA_SOX4

5,987

DC5_CD1C

5,852

DC3_CLU

5,306

DC1

4,625

DC2_TPPP3_LMNA

3,625

Level_1

Description

Similar clusters with shared features from level 2 were manually merged to one level higher in the hierarchy to determine clustering.

Annotation Method

manual

Cell Labels (1)

Cells (145,941)

Myeloid

145,941

Level_2

Description

Similar clusters with shared features from level 3 were manually merged to one level higher in the hierarchy to determine clustering.

Annotation Method

manual

Cell Labels (1)

Cells (145,941)

Dendritic

145,941

Level_3

Description

Similar clusters with shared features from level 4 were manually merged to one level higher in the hierarchy to determine clustering.

Annotation Method

manual

Cell Labels (2)

Cells (145,941)

DC

120,656

pDC

25,285