Human PBMC atlas - T/NK proliferating cells

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Cell Metadata

Prolif NK CD16 adaptive activ NR4A2

Full Name: proliferating NR4A2+ activated CD16-positive, CD56-dim adaptive natural killer cell, human
Closest Ontology Term: CD16-positive, CD56-dim natural killer cell, humanCL:0000939
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: CD16-positive, CD56-dim natural killer cell, humanCL:0000939
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster expresses canonical CD16+ adaptive NK cell markers in addition to NR4A2 marker of activation and markers of proliferation
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: NR4A2
Canonical Marker Genes: FCGR3A, KLRC2, MKI67, TOP2A, STMN1
Rationale: Cluster expresses canonical CD16+ adaptive NK cell markers in addition to NR4A2 marker of activation and markers of proliferation
Rationale DOI: https://doi.org/10.1016/j.coi.2023.102285 10.4049/jimmunol.1002732

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual

Full Name: proliferating NR4A2+ activated CD16-positive, CD56-dim adaptive natural killer cell, human
Closest Ontology Term: CD16-positive, CD56-dim natural killer cell, humanCL:0000939
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: CD16-positive, CD56-dim natural killer cell, humanCL:0000939
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster expresses canonical CD16+ adaptive NK cell markers in addition to NR4A2 marker of activation and markers of proliferation
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: NR4A2
Canonical Marker Genes: FCGR3A, KLRC2, MKI67, TOP2A, STMN1
Rationale: Cluster expresses canonical CD16+ adaptive NK cell markers in addition to NR4A2 marker of activation and markers of proliferation
Rationale DOI: https://doi.org/10.1016/j.coi.2023.102285 10.4049/jimmunol.1002732

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual