Human PBMC atlas - T/NK proliferating cells

Prolif T CD4 naive quiesc

Full Name: proliferating quiescent naive thymus-derived CD4-positive, alpha-beta T cell
Closest Ontology Term: naive thymus-derived CD4-positive, alpha-beta T cellCL:0000895
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: naive thymus-derived CD4-positive, alpha-beta T cellCL:0000895
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster expresses canonical naive CD4 T cell markers and ribosomal genes suggesting quiescence. Additionally expresses markers of proliferation.
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: unknown
Canonical Marker Genes: CD4, RPS10, CCR7, MKI67, TOP2A, STMN1
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: Cluster expresses canonical naive CD4 T cell markers and ribosomal genes suggesting quiescence. Additionally expresses markers of proliferation.
Rationale DOI: https://doi.org/10.1073/pnas.0400606101

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual